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Titlebook: Genetic Engineering; Principles and Metho Jane K. Setlow Book 1990 Plenum Press, New York 1990 Retinoblastom.Translation.cloning.gene expre

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Regulation of Alternative Splicing,the regulation of the synthesis of various biologically important proteins. The simplest form of such regulation results from the tissue- or temporal-specific splicing events that lead alternatively to functional (protein coding) and nonfunctional (not protein coding) RNAs, but other events, such as
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Control of Translation Initiation in Hamnalian Cells,he translational machinery and the translational efficiency of the mRNA. The former involves gene transcription, mRNA processing, mRNA transport to the cytoplasm, and the half-life of the mRNA. Translational efficiency is determined by mRNA structure, the level and activity of the translational mach
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The Isolation and Identification of cDNA Genes by Their Heterologous Expression and Function,ructure. However, frequently the purification of sufficient amounts of homogeneous protein for amino acid sequence determination is technically and logistically not feasible. In these situations, if the gene’s phenotype has been well characterized, an alternative gene isolation strategy may be utili
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