Titlebook: GTPases in Biology I; Burton F. Dickey,Lutz Birnbaumer Book 1993 Springer-Verlag Berlin Heidelberg 1993 Calcium.DNA.Nucleotide.RNA.biochem

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Eukaryotic Translation Factors Which Bind and Hydrolyze GTPosome. A curious feature of eIF-5 is that it also possesses a ribosome-dependent GTPase activity which is required in model assays using eIF-2A in place of eIF-2 to form initiation complexes (. et al. 1975; . et al. 1975).

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Structural Conservation of Ras-Related Proteins and Its Functional Implicationsds (usually the DTAGQE sequence around position 61) and low stringency hybridization with already isolated probes, sometimes from distant organisms. Another important strategy consisted in the biochemical isolation of small GTPases from various tissues on the basis of their GTP/GDP-binding ability a

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Structural and Mechanistic Aspects of the GTPase Reaction of H-ras p21 of crystallographic analyses of various p21-nucleotide complexes, discuss the kinetic mechanism of the GTPase reaction in detail, and relate these to the molecular mechanism of the intrinsic GTPase reaction. We further extend these considerations to the GTPase reaction in the presence of GTPase act

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https://doi.org/10.1007/978-3-8349-3542-7e P site of the ribosome (Fig. 1b). Translocation is also accompanied by GTP hydrolysis, with EF-G-GDP being released from the ribosome. The third elongation factor, EF-Ts, catalyzes the exchange of GTP for GDP on EF-Tu.

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https://doi.org/10.1007/978-981-13-1639-5s and cytoplasmically disposed coat proteins that serve to define the vesicle constituents. The second, and equally important step, is the process by which each vesicle is brought into contact with the appropriate target organelle. While cytoskeletal elements are involved in the transport of vesicle

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https://doi.org/10.1007/978-1-349-19215-1cle affect the dynamics of actin filaments and microtubules and could be used as a means of regulation in vivo. It is hoped that by comparing the detailed mechanisms of different GTPases and of the Factin/microtubule systems, fruitful ideas will emerge to better understand the different biological f