| 書(shū)目名稱 | G Protein-Coupled Receptors | | 副標(biāo)題 | Immobilization and A | | 編輯 | Xinfeng Zhao,Qian Li,Jia Quan | | 視頻video | http://file.papertrans.cn/381/380010/380010.mp4 | | 概述 | Describes progress in functional immobilization of G protein-coupled receptor.Addresses pharmacological parameters in protein-drug interactions.Reviews the applications of protein immobilization | | 叢書(shū)名稱 | SpringerBriefs in Molecular Science | | 圖書(shū)封面 |  | | 描述 | This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the “post-structural biology” era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other | | 出版日期 | Book 2023 | | 關(guān)鍵詞 | GPCRs; Oriented immobilization; Drug-ligand interaction;; Natural products; Drug discovery | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-99-0078-7 | | isbn_softcover | 978-981-99-0077-0 | | isbn_ebook | 978-981-99-0078-7Series ISSN 2191-5407 Series E-ISSN 2191-5415 | | issn_series | 2191-5407 | | copyright | The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023 |
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