Titlebook: Essentials of Bioinformatics, Volume I; Understanding Bioinf Noor Ahmad Shaik,Khalid Rehman Hakeem,Ramu Elango Book 2019 Springer Nature Sw

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https://doi.org/10.1007/978-3-642-46893-3pharmacological efficacy was well established. Eventhough, advancement in drug discovery approaches, drug development is still an expensive, lengthy, and difficult process associated with a high attrition rate. For developing single drug it may take about 10–15?years and cost $1–1.8 billion. This pr

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Biljana Cubaleska,Markus Schneiderdge about the preferred molecular orientation helps in predicting the binding affinity between two test molecules. MD is the most widely used method in structure-based drug designing and also in biochemical investigations. There are two major steps involved in MD procedure: first is a search algorit

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The Advice Taker/Inquirer (AT/I),. The advancement of computational algorithms has allowed us to calculate the theoretical possibility of a successful PCR by designing highly specific and sensitive primers before starting expensive laboratory assays. Variety of web servers freely available for designing primer sequences and computa

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https://doi.org/10.1007/978-1-4612-5769-1, theoretical development in computer science opened new windows for system modeling. A growing interest of physicist to solve complex biological processes and regulation mechanism underlying unknown pathway made a significant contribution in optimization techniques. In this chapter, we focused on a

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Sequence Databases,ized databases. As of today, there are many databases which host the specific information about particular genes and proteins from diversified biological sources like humans, animals, plants, and microbes. These databases are continuously being enriched and updated with the latest research informati

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Biological 3D Structural Databases,positories known as structural databases are created where a plethora of structures are deposited and refined yearly. This chapter presents these databases and highlights their characteristic features in addition to related servers that help in storing, analysis, comparison, and classification of th