Titlebook: Epigenetics - A Different Way of Looking at Genetics; Walter Doerfler,Petra B?hm Book 2016 Springer International Publishing Switzerland 2

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Formation of Bacterial Lineages in , by Epigenetic Mechanisms,r cases, the basis of bacterial lineage formation is more complex and involves the formation of heritable DNA methylation patterns. In ., a pathogen of humans and livestock, lineage formation plays roles in host colonization, bacteriophage resistance, motility, biofilm formation, and adaptive resistance to antibiotics.

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Formation of Bacterial Lineages in , by Epigenetic Mechanisms,ation to hostile and/or unpredictable environments. Lineage formation is often under epigenetic control, thus avoiding the burden of mutation. Epigenetic lineages can be formed whenever a cell-to-cell difference (e.g., generated by intrinsic noise) is propagated by a heritable feedback loop. In othe

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Lymphocyte Identity and Genomic Switches,atory lineages. In the early days, immunologists defined their functionality by expression of a small handful of signature genes. With the present extraordinary capabilities to gain genome-wide information on gene transcription, chromatin state, and transcription factor recruitment, we now come to a