Titlebook: Endocrinology of the Testis and Male Reproduction; Manuela Simoni,Ilpo T. Huhtaniemi Reference work 2017 Springer International Publishing

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https://doi.org/10.1007/0-387-32442-9itial space, and ultimately to the full development of the testis. Intriguingly, once determined, gonadal sex and therefore the male or female phenotype must be maintained through active repression of the molecular pathways determining the opposite sex. In this chapter, we will discuss the genetic a

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https://doi.org/10.1007/978-3-319-10867-4rization and nuclear translocation and binding to androgen response elements in the regulatory regions of AR target genes. Classic models of AR action view the AR chromatin-binding sites as upstream regulatory elements in gene promoters, but recent genome-wide methods have revealed that the AR regul

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Christoph Roman Clemens M.D.,Nicole Eternformation to subsequent generations and perpetuation of the species ultimately depend on GSC maintenance and the delicate balance between GSC self-renewal and differentiation. Spermatogenesis needs to be kept at a quantitatively normal level to sustain male fertility. Sertoli cells are the somatic

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