Titlebook: Drugs as Tools in Neurotransmitter Research; Alan A. Boulton,Glen B. Baker,Augusto V. Juorio Book 1989 Springer Science+Business Media New

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Content Lifecycles, Management, and Backupf models that highlight their usefulness and limitations. I have made my choice of models to discuss partly on the basis of their role (putative or actual) in modeling diseases, partly on their heuristic value in stimulating research, and partly because of my own personal interests. Some diseases wi

circumvent

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oxidize

Drugs as Tools in Neurotransmitter Research978-1-59259-617-1Series ISSN 0893-2336 Series E-ISSN 1940-6045

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Managing Device Drivers and PC Resourcesthe dopaminegic system is utilized to establish whether another drug exerts its pharmacological effects via that monoammergic system. .-Amphetamme is believed to act on the dopaminergic system because some, but not all, pharmacological effects are inhibited by antidopammergic agents

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GEM

Neurotoxins that affect central indoleamine neurons,anski et al., 1956; De Robertis, 1964; Twarog and Page, 1953; Zieher and De Robertis, 1963) based on biochemical determinations of this amine in different brain regions. These studies were rapidly followed by the use of histofluorescent microscopy (Anden et al., 1965, 1966, 1967; Dahlstrom and Fuxe,

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Toxins Affecting Cholinergic Neurons, and bacteria have evolved toxins that selectively interfere with cholinergic transmission is an indication of the relative importance of ACh as a neurotransmitter substance. In order for a toxin to be biologically effective, it must produce a sustained action at low concentrations. The high potency