Titlebook: Drugs Targeting B-Cells in Autoimmune Diseases; Xavier Bosch,Manuel Ramos-Casals,Munther A Khamash Book 2014 Springer Basel 2014 Cryoglobu

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Daniel B. Cornfield,Randy Hodsonease has long been regarded as very unlikely to be successful. In 2002 the first report was published in a case series of five patients that advocated B cells as a therapeutic target, spurred by a report of Takemura et al., who even suggested that the activation of T cells in the rheumatoid synovium was B cell-dependent.

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Building an International Sociology of Workditions such as steroid-resistant and dependent sarcoidosis, Beh?et disease with retinal vasculitis, chronic hepatitis C virus-associated polyarteritis nodosa, highly active refractory Takayasu arteritis, and Henoch–Sch?nlein purpura nephritis.

Outwit

B-Cell Targeted Therapies in Rheumatoid Arthritis,ease has long been regarded as very unlikely to be successful. In 2002 the first report was published in a case series of five patients that advocated B cells as a therapeutic target, spurred by a report of Takemura et al., who even suggested that the activation of T cells in the rheumatoid synovium was B cell-dependent.

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,B-Cell Targeted Therapies in Primary Sj?gren Syndrome,the evidence from controlled trials has suggested that tumour necrosis factor blockers are not efficacious in primary SS, the use of B-cell targeted agents (rituximab, epratuzumab, belimumab) may be more promising therapies. However, the potential risks and benefits of these new agents must be always weighted carefully.