Titlebook: Drug Delivery to the Brain; Physiological Concep Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lan Book 20141st edition American Associati

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Drug Discovery Methods for Studying Brain Drug Delivery and Distributionre is now more focus on measuring or estimating target unbound drug concentrations in the brain and evaluating the quantitative aspects of drug transport across the blood–brain barrier (BBB). The techniques for investigation of the rate and extent of BBB transport of new chemical entities (NCEs) are

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Intranasal Drug Delivery to the Brainriers (BCSFB) that separate the blood from brain interstitial and cerebrospinal fluids, respectively. New strategies to circumvent the BBB are greatly needed to utilize polar pharmaceuticals and large biotherapeutics for CNS disease treatment because the BBB is typically impermeable to such compound

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