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Titlebook: Drug Action at the Molecular Level; G. C. K. Roberts Book 1977 Institute of Biology Endowment Trust Fund 1977 drug.research.Symposium

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31#
發(fā)表于 2025-3-26 22:24:20 | 只看該作者
32#
發(fā)表于 2025-3-27 03:04:40 | 只看該作者
Strukturierung des Therapieablaufsnd then attempt to explain the sequence of events which connect that interaction with the physiological response. It is commonly envisaged that the binding of the drug to its receptor provokes conformational changes in the latter which act as the immediate trigger leading to the biological effect. O
33#
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發(fā)表于 2025-3-27 11:27:14 | 只看該作者
35#
發(fā)表于 2025-3-27 16:30:05 | 只看該作者
https://doi.org/10.1007/978-3-662-10791-1 identical with, the sodium pump activity of cell membranes. ., this enzyme pumps sodium out of and potassium into the cell and it has therefore, during its transport cycle, access to both sides of the cell membrane (Post .. 1969). The transport function of Na. + K. — ATPase is required for volume c
36#
發(fā)表于 2025-3-27 21:17:01 | 只看該作者
Strategische Dimensionen der Virtual Realityshed by Sutherland and his associates (Sutherland and Rall, 1960) that the only ingredients necessary to elicit a hormonal effect on the enzyme were magnesium ion, ATP, hormone and membranes bearing the enzyme. This seemingly simple system, in which hormone was shown to increase the . of adenylate c
37#
發(fā)表于 2025-3-28 01:36:43 | 只看該作者
38#
發(fā)表于 2025-3-28 03:24:25 | 只看該作者
Biological Council Symposia on Drug Actionhttp://image.papertrans.cn/e/image/283023.jpg
39#
發(fā)表于 2025-3-28 09:00:02 | 只看該作者
The receptor site for chloramphenicol , and ,for a review, see Pestka, 1971). It was the first antibiotic to be synthesised by chemical methods (Controulis, Rebstock and Crooks, 1949). The molecule has a relatively simple structure, which consists of a propanediol moiety (III), carrying a p-nitrobenzene side-chain (I) and a dichloroacetyl side-chain (II) (Fig. 10.1).
40#
發(fā)表于 2025-3-28 11:17:24 | 只看該作者
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