Titlebook: Drosophila Models for Human Diseases; Masamitsu Yamaguchi Book 2018 Springer Nature Singapore Pte Ltd. 2018 Gene function.Drug screen.Meta

abduction

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Adult Intestine Aging Model,cells. The aged adult intestine shows apparent characteristics such as multilayering of absorptive cells, misexpression of cell type-specific genes, and hyperproliferation of stem cells. Recent studies have revealed various gene networks responsible for progression of these aged phenotypes. The mole

nocturia

,Alzheimer’s Disease Model System Using ,,and memory defects, as well as massive neurodegeneration phenotype. The presence of intracellular neurofibrillary tangles (NFTs) and extracellular amyloid plaques, called senile plaques (SPs), and brain atrophy are typically observed in the brains of AD patients. It has been over 20?years since the

明智的人

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Misnomer

Esophagitis

Charcot-Marie-Tooth Disease Models,and motor neurons. Although more than 80 CMT-causing genes have been identified to date, an effective therapy has not yet been developed for this disease. Since . does not have axons surrounded by myelin sheaths or Schwann cells, the establishment of a demyelinating CMT model is not appropriate. In

extinguish

as a Model to Gain Insight into the Role of lncRNAs in Neurological Disorders,h spanning from 200?bp up to several kilobases. To date, we have a limited understanding of the lncRNA function, but a huge number of evidences have suggested that lncRNAs represent an outstanding asset for cells. In particular, temporal and spatial expression of lncRNAs appears to be important for

Hirsutism

Muscular Dystrophy Model,e genes responsible for the structure and functioning of muscles. There are many different types of MD which have a wide range from mild symptoms to severe disability. Some types involve the muscles used for breathing which eventually affect life expectancy. This chapter provides an overview of the

filicide

As a Cancer Model,evelopment of genetic mosaic technique in . has enabled us to recapitulate basic aspects of human cancers, including clonal evolution, tumor microenvironment, cancer cachexia, and anticancer drug resistance. The mosaic technique has also led to the discovery of important tumor-suppressor pathways su