Titlebook: Diabetes and Cardiovascular Disease; Michael Johnstone,Aristidis Veves Book 2023Latest edition The Editor(s) (if applicable) and The Autho

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PPARs and Their Emerging Role in Vascular Biology, Inflammation and Atherosclerosisal programs related to energy balance and related pathways. Three major isotypes exist: PPAR-γ, PPAR-α, and PPAR-β/δ. PPAR-γ is predominant in adipose tissue promoting insulin sensitivity and weight gain. Also, its presence in the renal tissue promotes water retention. In contrast, PPAR-α receptors

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Diabetes and Thrombosiscondary in part to (1) increased platelet reactivity; (2) increased thrombotic activity reflecting increased concentrations and activity of coagulation factors and decreased activity of antithrombotic factors; and (3) decreased fibrinolytic system capacity resulting from overexpression of plasminoge

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Adiponectin, Diabetes, and the Cardiovascular System endocrine organ that is involved in the regulation of insulin sensitivity, glucose and lipid metabolism, as well as cardiovascular homeostasis. Adiponectin is the most abundant circulating adipocytokine, principally secreted from adipose tissue. This adipocytokine plays a crucial role in the endocr

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preeclampsia

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The Role of Sleep Apnea in Diabetes Mellitus and Cardiovascular Diseaseing evidence supports not only an association but also a causal relationship between types of SDB and the incidence and morbidity of hypertension, coronary heart disease, arrhythmia, heart failure, stroke, diabetes, and possibly high-risk pregnancy conditions. The recognition and treatment of SDB ma

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The Metabolic Syndrome and Vascular Diseased manifests through mechanisms of insulin resistance, pancreatic, hepatic, renal, and adipose dysfunction, altered gastrointestinal microbiota, oxidative stress, and systemic inflammation. A twofold increase in cardiovascular disease and a fivefold increase in the risk for type 2 diabetes are observ