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Titlebook: Detection of Mitochondrial Diseases; Frank Norbert Gellerich,Stephan Zierz Book 1997 Springer Science+Business Media Dordrecht 1997 genome

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書目名稱Detection of Mitochondrial Diseases
編輯Frank Norbert Gellerich,Stephan Zierz
視頻videohttp://file.papertrans.cn/270/269238/269238.mp4
叢書名稱Developments in Molecular and Cellular Biochemistry
圖書封面Titlebook: Detection of Mitochondrial Diseases;  Frank Norbert Gellerich,Stephan Zierz Book 1997 Springer Science+Business Media Dordrecht 1997 genome
描述In October 1995, the 1st Colloquium on Mitochondria andMyopathies in Halle/Saale was organized in Halle/Saale by the editorsof this focused issue. The meeting took up what might be called anEast German tradition: from 1976 to 1990 Andreas Schmidt organizedseven clinically orientated Colloquia on Myology in Jena, and from1974 to 1990 a series of twelve Colloquia on Mitochondria focused onbasic research aspects was arranged by Wolfgang Kunz in Magdeburg. Atthose meetings, East Germany was a mediator between East European,West European and American scientists. In continuation of thistradition, scientists from more than 17 countries working onmitochondria as neurologists, biochemists, geneticists, or asphysiologists came to Halle. The title of the colloquium indicated thecombination of both basic and clinical mitochondrial research. Themost important contributions of this meeting are now published in thisfocused issue. We thank all authors for their patience and cooperationthat have made it possible to produce this unique collection of papersrepresenting current knowledge on detection of mitochondrial causes ofdiseases. We especially thank Prof. N.S. Dhalla for making it possibleto pub
出版日期Book 1997
關(guān)鍵詞genome; mitochondria; paper
版次1
doihttps://doi.org/10.1007/978-1-4615-6111-8
isbn_softcover978-1-4613-7800-6
isbn_ebook978-1-4615-6111-8
copyrightSpringer Science+Business Media Dordrecht 1997
The information of publication is updating

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Non-invasive quantitative ,P MRS assay of mitochondrial function in skeletal muscle ,e resolution . NMR measurements of phosphocreatine, inorganic phosphate and ATP resonances were conducted on human forearm flexor muscle during involuntary twitch contraction at eight different frequencies. Mitochondrial and glyco(geno)lytic ATP synthesis fluxes, and the cytosolic free energy of ATP
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Phosphorus metabolite distribution in skeletal muscle: Quantitative bioenergetics using creatine anaact cell through the advent of .P-NMR spectroscopy. The near-equilibrium formulation for creatine kinase (CK) has been used for the calculation of ADP. and ATP chemical potential in many of these studies. However, control of the bulk cytoplasmic PCr/Cr ratio by the ATP/ADP ratio through CK implies t
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Fluxes through cytosolic and mitochondrial creatine kinase, measured by P-31 NMR kinase (CK) iso-enzyme family has a multi-faceted role in cellular energy metabolism and is characterized by a complex pattern of tissue-specific expression and subcellular distribution. In mammalian tissues, there is always co-expression of at least two different CK isoforms. As a result, previous
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Small scale preparation of skeletal muscle mitochondria, criteria of integrity, and assays with refereparation was developed for 25–100 mg tissue with pigeon breast muscle as model organ. The yield was 40%. Data collected during the developmental work were used to evaluate criteria of mitochondrial quality. The cytochrome c conservation, i.e. cytochrome c per mitochondrial quantity in the preparat
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