Titlebook: Dendritic Cells; Methods and Protocol Vanja Sisirak Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to S

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Matthias E. Liechti,Friederike Holzehat support DC development, such as FMS-like tyrosine kinase 3 ligand (FLT3L) and granulocyte-macrophage colony-stimulating factor (GM-CSF) (Guo et al., J Immunol Methods 432:24–29, 2016). In response to these growth factors, DC progenitors expand and differentiate, while other cell types die during

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Current Topics in Behavioral Neurosciencesity. DCs orchestrate protective responses against pathogens and tumors while mediating tolerance to host tissues. Evolutionary conservation between species has allowed the successful use of murine models to identify and characterize DC types and functions relevant to human health. Among DCs, type 1

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Disarmament, Arms Control and Arms Raceammation. In vivo, monocytes are exposed to various signals that modulate their commitment toward macrophage or dendritic cell fate. Classical culture systems for human monocyte differentiation yield either macrophages or dendritic cells, but not both populations in the same culture. In addition, mo

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Disarmament, Arms Control and Arms Racesets collaboratively initiate and orchestrate innate and adaptive immune responses. Recent advances in our ability to investigate cellular transcription, signaling, and function at the single-cell level have opened opportunities to examine heterogeneous populations at unprecedented resolutions. Cult

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André Thomas,Alexander Pfeiffertigen phagocytosis and T cell activation across different inflammatory settings such as tumor development. As specific DC identity and how these cells interact with their neighbors is still not fully understood, it remains a challenge to unravel DC heterogeneity, particularly in human cancers. In th

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Vanja SisirakIncludes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts