Titlebook: DNA Repair of Cancer Stem Cells; Lesley A Mathews,Stephanie M Cabarcas,Elaine M. Hu Book 2013 Springer Science+Business Media Dordrecht 20

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Introduction to Cancer Stem Cells,search has focused on these cells, their properties and potential targets within these cells for cancer treatment. This chapter will introduce the CSC theory, discuss important properties of these cells, and highlight the need to target them for improved patient outcome.

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The Future of DNA Repair and Cancer Stem Cells,tments. The following is a summary of the previous chapters presented in this text with an emphasis on the future of CSCs and their potential contribution to the development and identification of novel therapies and targets.

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utions, pharmaceutical companies, medical professionals, govThe existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence sup

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https://doi.org/10.1007/978-3-642-02956-1nsic environmental factors. BCSC are resistant to chemotherapy and radiation therapy. The therapeutic resistance of BCSC derives from multiple mechanisms. In this chapter, we discussed the potential mechanisms for enhanced DNA repair of BCSC in the response to DNA damage.

Carcinogen

DNA Repair Mechanisms in Breast Cancer Stem Cells,nsic environmental factors. BCSC are resistant to chemotherapy and radiation therapy. The therapeutic resistance of BCSC derives from multiple mechanisms. In this chapter, we discussed the potential mechanisms for enhanced DNA repair of BCSC in the response to DNA damage.

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