Titlebook: Cytotoxic Drug Resistance Mechanisms; Robert Brown,Uta B?ger-Brown Book 1999 Humana Press 1999

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https://doi.org/10.1007/978-1-4842-2424-3rm glutathione disulfide (GSSG), making protons available to neutralize reactive oxygen species (.). In vivo, reduction of GSSG is catalysed by glutathione reductase, efficiently regenerating high intracellular GSH levels (.)

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https://doi.org/10.1007/978-3-319-62773-1gnition as the first of a new class of oncogene able to prolong survival by inhibiting programmed cell death (apoptosis) and (b) the discovery of many additional related genes/proteins some of which, like Bcl-2, inhibit apoptosis, whereas others, such as Bax, conversely promote cell death (.) (.).

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