Titlebook: Cytokine Knockouts; Scott K. Durum,Kathrin Muegge Book 19981st edition Springer Science+Business Media New York 1998 Colon.Vivo.cytokine.c

壯觀(guān)的游行

https://doi.org/10.1057/978-1-137-54786-6tact organism. Specifically, the availability of these knockout mice has made it possible to determine the importance of the interferons in the resistance to infections and in some specific functions of the immune system. These investigations, to be briefly reviewed in this chapter, led to some unexpected findings.

愛(ài)好

Piety in the Pocket: An Introduction,in (LAP, equivalent to NF-IL6) and liver inhibitory protein (LIP) by alternative usage of two AUG initiation codons within the same open reading frame .. LIP contains the DNA binding and dimerization domains but is devoid of the N terminal transcriptional activation domain, and therefore behaves as an antagonist of LAP-induced transcription.

deface

circuit

Lymphoid Development and Function in IL-7R-Deficient Mice,imilar fashion, it has been established that the CD44.CD25. fraction of CD4.CD8. thymocytes, comprising <1% of the total thymocyte population, is IL-7 responsive, whereas the predominant CD4.CD8. thymocyte subpopulation is not (.).

Heterodoxy

Knockouts of Interferons, Interferon Receptors and Interferon Signaling Components,tact organism. Specifically, the availability of these knockout mice has made it possible to determine the importance of the interferons in the resistance to infections and in some specific functions of the immune system. These investigations, to be briefly reviewed in this chapter, led to some unexpected findings.

Observe

NF-IL6 Knockout Mice,in (LAP, equivalent to NF-IL6) and liver inhibitory protein (LIP) by alternative usage of two AUG initiation codons within the same open reading frame .. LIP contains the DNA binding and dimerization domains but is devoid of the N terminal transcriptional activation domain, and therefore behaves as an antagonist of LAP-induced transcription.

Fracture

Disruption of the LIF Receptor,irst binds CNTF receptor (CNTFR) and this complex then interacts with LIFR and gp130 .. Therefore, of the known ligands, the absence of LIFR would completely disrupt activity of LIF, CNTF, and CT-1, and would affect some OSM activity.