Titlebook: Current and Future Immunosuppressive Therapies Following Transplantation; Mohamed H. Sayegh,Giuseppe Remuzzi Book 2001 Springer Science+Bu

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Monoclonal Antibody Targeting of the Il-2R ComplexT3, a murine anti-CD. monoclonal antibody, was introduced in 1986. The mechanism of action of OKT3 consists of T cell depletion and CD. modulation. While the polyclonal agents and OKT3 induce effective immunosuppression, they are also associated with opportunistic infections and post transplant lymp

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Immunomodulatory Function of MHC Peptidesugh many diverse mechanisms including inhibition of cell cycle progresssion, altered signal transduction and the induction of apoptosis. The potential, therefore, exists that peptides, or compounds derived from them, may represent an exciting new form of immunotherapy.

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