Titlebook: Coronary Angioplasty: A Controlled Model for Ischemia; P. W. Serruys (Chief Cardiac Catheterization Labor Book 1986 Martinus Nijhoff Publi

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Effects of acute myocardial ischemia and reperfusion in conscious animals,ronary blood flow, arising from either arterial spasm, trombotic events or platelet aggregation [1]. In addition short ischemic insults are routinely inflicted to the myocardium in patients with coronary artery disease during angioplasty.

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Intracoronary electrocardiogram during transluminal coronary angioplasty,schaemia in anterior and lateral areas. The coronary guide wire employed for PTCA can be used as an intracoronary ECG lead [1]. The ECG derived from it reflects the myocardium distal to the stenosis to be dilated.

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Left ventricular filling during acute ischemia,partite. Immediately after mitral valve opening a rapid filling phase starts and lasts about 200 msec, followed by slow filling or diastasis, the duration of which is dependent on the heart rate and finishes with left atrial contraction.

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The Scientist as a Concertmasteroncern as the number of dilated vessels and the duration of balloon inflation tend to increase, thereby enhancing both the extent and the severity of ischemia. The risk exists that the damage induced by the intervention may exceed its benefit.

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Book 1986bstmction. From the available evidence it can be estimated, that this thera- peutic tool will get even more additional momentum of many ten-thousands of patients to be treated in the next few years, due to a growing fraction of patients who are candidates for this intervention. Information about the

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