Titlebook: Computer and Information Science Applications in Bioprocess Engineering; Antonio R. Moreira,Kimberlee K. Wallace Book 1996 Kluwer Academic

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978-94-010-6564-1Kluwer Academic Publishers 1996

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Computer-Based Studies on Bioprocess Engineering examined. Basic numerical tools and details on least squares estimation, particularly statistical analysis of estimates are discussed. A process simulator of the dynamics of non-linear systems is presented and shown through the application to case studies to be an efficient tool for teaching and re

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Multivariable Control of a Continuous Culturecontrol. This control loop was coupled with ammonium control using an on-line ammonia electrode suspended above a pH-adjusted sample stream from the fermentor. The dilution rate of the culture was the sum of the two individual feed rates. The advantages and implications of multivariable feedback con

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Nonlinear Oscillations in Bioreaction Systemson pure culture with Monod type growth and linearly varying yield coefficient, was applied to pure culture of substrate-inhibition type growth and found to produce performance improvements of similar magnitude.

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The Design Approach of Multiproduct Plantss approach. In this paper an introduction to this topic is carried out, pointing out the basic methods and the computer design resolutions. An example plant representing a biotechnological process is used as a basis for the application of the methods.

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Strategies for Bioreactor Scale-Up the understanding of the fundamental phenomena, at least for the simpler cases. For more complicated heterogeneous systems the employment of various rules of thumb is still widely practised. A summary of various strategies for bioreactor scale-up is given below.

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Statistical Design and Analysis of Experiments The strategy employs a screening Plackett-Burman design that selects two of six factors. Then a two- level factorial design is carried out in order to define a search direction. The optimizing search is done employing the Simplex algorithm. A surface response quadratic model in three factors is gen

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Simulation of a Complex Biotechnological Process Using an Object-Oriented Knowledge-Based Systemering software. The features of object- oriented programming for the simulation of complex systems are demonstrated on an example of the simulation of ethanol plant using the real-time expert system shell G2.