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Titlebook: Computational Modelling of the Human Islet Amyloid Polypeptide; Katrine Kirkeby Skeby Book 2016 Springer International Publishing Switzerl

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書(shū)目名稱Computational Modelling of the Human Islet Amyloid Polypeptide
編輯Katrine Kirkeby Skeby
視頻videohttp://file.papertrans.cn/233/232837/232837.mp4
概述Nominated as an outstanding PhD thesis by Aarhus University, Denmark.Provides a comprehensive review of the general amyloid literature, in particular that on human islet amyloid polypeptide.Includes d
叢書(shū)名稱Springer Theses
圖書(shū)封面Titlebook: Computational Modelling of the Human Islet Amyloid Polypeptide;  Katrine Kirkeby Skeby Book 2016 Springer International Publishing Switzerl
描述.This thesis offers readers a comprehensive introduction to amyloid proteins and the computational methods used with them. Katrine Skeby critically assesses and compares both the literature and the experiments performed by other researchers, which further elevates the quality and relevance of her own work. Amyloid proteins are highly complex, and this research provides unparalleled insights, especially with regard to the origin of cytotoxicity and to developing technologies for early detection, revealing in detail the molecular mechanisms behind hIAPP behavior. Several studies within the thesis answer difficult questions which promote future research into the properties of amyloid proteins..
出版日期Book 2016
關(guān)鍵詞Alzheimer‘s disease; Amylin; Amyloid; Amyloid fibrils; Free energy calculations; Human islet amyloid poly
版次1
doihttps://doi.org/10.1007/978-3-319-20040-8
isbn_softcover978-3-319-79293-4
isbn_ebook978-3-319-20040-8Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer International Publishing Switzerland 2016
The information of publication is updating

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Computational Modelling of the Human Islet Amyloid Polypeptide
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https://doi.org/10.1007/b138114esis is concerned with elucidating the biological processes concerning amyloid proteins, more specifically, the peptide hormone human islet amyloid polypeptide (hIAPP), which is involved in glucose homeostasis and deposits in the pancreas of T2DM patients.
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