Titlebook: Comorbidity; Symptoms, Conditions Rhonda Brown,Einar Thorsteinsson Book 2020 The Editor(s) (if applicable) and The Author(s), under exclusi

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Models of Comorbidity,. As a result, we know little about the extent to which comorbidity is relevant to our understanding of single disorders and conditions; the mechanisms likely to underpin the development of the comorbidities; and the nature of the interactions between specific risk factors and comorbid disorders.

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Overview of the Comorbidity Between Medical Illnesses and Overweight/Obesity, the role of the metabolic syndrome in these illnesses. The importance of causality of comorbid conditions at early, middle and late stages of disease is emphasised, as interventions targeting causalities at each of these times are likely to have the greatest impact on lessening the burden of overweight and obesity on affected individuals.

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Arousal States, Symptoms, Behaviour, Sleep and Body Temperature,phase-shift in the sleep-wake cycle. However, an elevated BT can additionally lead to activation of the inflammatory response system (e.g. cytokine secretion), which may represent another possible mechanism by which the aforementioned states, symptoms, disorders and behaviour can develop.

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