Titlebook: Clostridium difficile; Klaus Aktories,Tracy D. Wilkins (Director of Biote Book 2000 The Editor(s) (if applicable) and The Author(s), under

Chemotherapy

Pathogenesis and Clinical Manifestations of , Diarrhea and Colitis,d O’T. 1935). The organism was given its name because it grew very slowly in culture and was difficult to isolate in pure culture. Its presence in the stool of 50% of healthy neonates suggested that . was a commensal not a pathogen, even though it was toxigenic in broth culture. Not long after its o

Prosaic

Treatment of ,-Associated Diarrhea and Colitis,oice has been toward greater use of metronidazolc rather than vancomycin because of increasing concern about vancomycin resistance in organisms such as the enterococcus (HICPAC 1995). However, this should not be interpreted to mean that improvements in therapy are not needed. There continue to be ma

財(cái)產(chǎn)

Genetics of , Toxins,nd, had been isolated previously from many patients, but had been ignored since it was “nonpathogenic”. Further investigation showed that toxic activity in culture filtrates from C. . was neutralized by C. . antisera. Thus the fortuitous cross-neutralizing activity of C. . antisera led to the discov

GIST

VEN

0070-217X ucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes.978-3-642-08668-7978-3-662-06272-2Series ISSN 0070-217X Series E-ISSN 2196-9965

衍生

最初

Georg Juckel,F. Schlagenhauf,A. Heinzidentified as the source of a cytotoxin found in the stool of patients with pseudomembranous colitis (B. et al. 1978). During the two decades since its rediscovery, a great deal has been learned about the pathophysiology, epidemiology, and management of . diarrhea, yet many challenges remain. At pre