Titlebook: Chromosome Segregation and Aneuploidy; Baldev K. Vig Conference proceedings 1993 Springer-Verlag Berlin Heidelberg 1993 Aneuploidie.Chromo

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Morphogenesis of the Mitotic and Meiotic Spindle: Conclusions Obtained From one System are not Necese, which ensures that the replicated chromosomes are segregated equivalently to two daughter cells. A major goal of cell division research is to understand the mechanism of spindle morphogenesis and how bipolarity is established.

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Chromosome Segregation and Aneuploidy,t 5% among stillborns and a dramatic 25% among miscarriages. The burden is too heavy to be taken lightly. Whereas cytogeneticists are capable of tracing the origin of the extra or missing chromosome to the contributing parent, it is not certain what factors are responsible for this ‘epidemic’ affect

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Structure of the mammalian centromere,irst described in 1894 by Metzner as the site at which chromosomes attached to the spindle apparatus (Metzner, 1894). Even before the genetic consequences of chromosome movement had been demonstrated, it was realized that the centromere was intimately involved in the distribution of nuclear material

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