Titlebook: Chromatin and Disease; Tapas K. Kundu,R. Bittman,P. Zwickl Book 2007 Springer Science+Business Media B.V. 2007 Chromatin Structure, Dynami

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0306-0225 pharmacology of the drugs targeting chromatin structure andIt is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription,

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Lifelong, Informal and Workplace Learning,e regulation of chromatin structure and function. Furthermore, various histone methyl-lysine demethylases (HLDMases) have been identified recently. In this chapter, histone H3 lysine 9 specific methyltransferases will be discussed as model enzymes involved in the regulation of chromatin function

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https://doi.org/10.1007/978-981-19-1235-1er cellular responses. Thus, histone variants and complexes involved in their exchange are likely to play major roles in controlling chromosomal architecture, and their deregulation is expected to be linked to cancers, infertility, mental disorders, ageing, and degenerative diseases

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