Titlebook: Cholesterol Transport Systems and Their Relation to Atherosclerosis; Armin Steinmetz,Hans Kaffarnik,Jürgen Schneider Conference proceeding

HILAR

輕觸

防止

颶風(fēng)

Removal of Low-Density Lipoproteins by Alternative Pathwaysvel must either decrease the rate of LDL formation or speed up the rate of its clearance from the plasma. The latter can be effected by increasing the specific LDL (or apo B, E) receptor activity in the liver, as is actually brought about by administration of bile acid sequestrants [3] and/or compactin or mevinolin [4].

出處

Receptors in the Regulation of Cholesterol Metabolism and specific amphipathic proteins (see [1] for review). The latter, the apolipoproteins, not only are responsible for maintaining the structure of the particle but also act as recognition signals for cell membrane receptors which trigger lipoprotein endocytosis [2]. The “classical” lipoprotein rece