| 書目名稱 | Cellular and Molecular Mechanisms in Hypertension | | 編輯 | Robert H. Cox | | 視頻video | http://file.papertrans.cn/224/223099/223099.mp4 | | 叢書名稱 | Advances in Experimental Medicine and Biology | | 圖書封面 |  | | 描述 | Hypertension is recognized to be one of the major risk factors for the development of peripheral vascular disease. The last decade has witnessed several major advances in therapy for hypertension, including the development of angiotensin-converting enzyme inhibitors and calcium channel blockers. These compounds have greatly improved the ability to control blood pressure and to reduce the impact of this risk factor on morbidity and mortality. In spite of these advances, cardiovascular disease remains a major health problem in most modern industrialized countries with related deaths exceeding those from all other causes combined. In contrast to these advances in therapy, our understanding of the basic mechanisms responsible for the pathogenesis of hypertension remains incomplete. Recent studies have produced new insights into the nature of the regulation of muscle contraction in both heart and blood vessels as well as the changes in muscle function that occur in hypertension. However, the effects of antihypertensive therapy, both in terms of restoring normal function and in producing reversal of hypertension-associated changes, has not been as thoroughly studied, especially in the va | | 出版日期 | Book 1991 | | 關(guān)鍵詞 | Calcium; Lipid; Pathogene; cardiovascular; development; enzymes; hypertension; lead | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4684-6015-5 | | isbn_softcover | 978-1-4684-6017-9 | | isbn_ebook | 978-1-4684-6015-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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