Titlebook: Cell to Cell Signals in Mammalian Development; S. W. Laat,J. G. Bluemink,C. L. Mummery Conference proceedings 1989 Springer-Verlag Berlin

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D’Ann R. Penner,Keith C. Ferdinandnding of basic biological problems in the areas of cell biology, endocrinology and development. As a first step toward the detailed analysis of growth factor activated cellular signalling mechanism, structural characterization of the RTK family resulted in complete primary structures of all known RT

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https://doi.org/10.1057/9780230621541vely. Recently, each of these CSFs has been purified to homogeneity, and cDNA clones encoding the factors have been exploited to produce previously unrealizable quantities of CSFs for experimental and therapeutic use. CSFs are already proving their efficacy in clinical trials and have numerous poten

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Organization and Systems Designaeras when injected into normal blastocysts. Embryonic stem (ES) cells established in vitro directly from isolated ICM’s (Martin 1981; Evans and Kaufman 1981) readily form normal chimaeras and as such are much closer to their embryonic origins. Further, EC cell lines require chemical induction of di

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Structure, Expression and Evolutionary Relationships of Murine Homebox Genes in the Hox 2 Clusternserve other domains, which may functionally interact with or compliment the homeodomain. Comparison of Hox 2.1 and Hox 2.6 to other mouse homeobox genes reveals close sequence identity to specific genes in the Hox 1 cluster, suggesting that these two loci arose by duplication and divergence of an a

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Temporal and Cellular Specificity of Expression of the Murine Homeobox-Containing Gene ,ected in germ cells. The larger of the transcripts is found in post-meiotic cells. A third size class of . transcripts are seen in embryos as early as 9.5 days of gestation. .. hybridization analysis of . expression in day 13.5 embryos reveals localizaton in the dorsal myelencephalon and the high ce