Titlebook: Cell Cycle in Development; Jacek Z. Kubiak Book 2011 Springer-Verlag Berlin Heidelberg 2011 Cell Cycle Regulation.Embryogenesis

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Greatwall Kinase, ARPP-19 and Protein Phosphatase 2A: Shifting the Mitosis Paradigm,sphorylation of hundreds of proteins required for cell division. However, if these phosphorylations are maintained during M-phase, they must be removed when cells exit mitosis. It has been surmised that an “antimitotic” phosphatase must be inhibited to allow mitosis entry and activated for returning

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The Role of RanGTP Gradient in Vertebrate Oocyte Maturation,an GTPase has an essential role in relaying the active role of chromosomes in their own segregation by the meiotic process. In addition to its conserved role as a key regulator of macromolecular transport between nucleus and cytoplasm, Ran has important functions during cell division, including in m

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Cell Cycle Control of Germ Cell Differentiation,y specialised cells are specified early during development and then migrate to the embryonic gonads where sex differentiation occurs. Germ cell sex differentiation is directed by the somatic gonadal environment and is characterised by two distinct cell cycle states that are maintained until after bi

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Protein Kinases and Protein Phosphatases that Regulate Meiotic Maturation in Mouse Oocytes,s of chromosome segregation without an intervening round of DNA replication and an arrest at metaphase of meiosis II (MII); fertilization triggers exit from MII and entry into interphase. During meiotic resumption, there is a burst of protein phosphorylation and dephosphorylation that dramatically c

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Function of the A-Type Cyclins During Gametogenesis and Early Embryogenesis,h the cell cycle. Among the cyclins, those known as the A-type cyclins are unique in that in somatic cells, they appear to function at two stages of the cell cycle, at the G1-S transition and again as the cells prepare to enter M-phase. Higher vertebrate organisms have two A-type cyclins, cyclin A1

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0080-1844 ate of the art in this hot topic..This book focuses on the intersection between cell cycle regulation and embryo development. Specific modifications of the canonical cell cycle occur throughout the whole period of development and are adapted to fulfil functions coded by the developmental program. De