Titlebook: Cardiac Glycosides; Günter Bodem,Hans J. Dengler Conference proceedings 1978 Springer-Verlag Berlin Heidelberg 1978 Bypass.Herzglykosid.as

WATER

persistence

Digoxin Pharmacokinetics and Their Relation to Clinical Dosage Parameters,cal basis (Augsberger, 1951, 1954). It is particularly noteworthy that these calculations were performed without any knowledge of drug concentrations but by the use of analysis of clinical data on drug effects only; this is a rather modern approach.

哀悼

Hiatal-Hernia

A New Simple Assay for Determining Digoxin Serum Levels,r now). In the meantime, work on an enzyme immunoassay has been completed; therefore, we found it more appropriate to report on this assay, thus justifying the announcement of a new assay for determining digoxin levels. Because the ELISA will always be compared with the RIA, some information on the

消散

Chloroform-Extractable and Polar Metabolites Examined With Different Assays, A similar pattern of methyldigoxin was described by Rietbrock and Abshagen (1973) and Abshagen et al. (1974). The chemical nature of these polar metabolites were thought to be the sulfuric and glucuronic acid conjugates of the bis- and monoglycosides and of aglucone, as first proposed by Repke et a

PAN

Hyperplasia

Occurence and Chemical Nature of Polar Water-Soluble Digoxin Metabolites,etabolite fraction detectable in the urine, this phenomenon being first described in 1972 by Dwenger-Haberland (Dwenger and Haberland, 1972). The polar fraction in urine increases to a maximum 4 h after ingestion of the glycoside. At this time, half of the renally excreted amount is not extractable