Titlebook: Cancer Stem Cells; Methods and Protocol Gianpaolo Papaccio,Vincenzo Desiderio Book 2018 Springer Science+Business Media LLC 2018 Tumor type

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1064-3745 key implementation advice from the expertsThis detailed volume gathers a comprehensive collection of methods, protocols, and procedures used for the identification, characterization, and selection of cancer stem cells. These include surface marker expression, side population, spheres formation, ALD

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International Year of Planet Earthto identifying better treatment options. While the CSCs hypothesis highlights the need for a specific tumor target, patient-derived xenografts (PDXs) should also be considered for drug development as they better represent tumor heterogeneity and the environment in which a tumor develops.

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New Frontiers in Lifestyle-Related Diseasesew tumors. Among many other capabilities such as migration or immune escape, CTCs require tumor-forming capacities and can therefore be considered stem cell-like cells. This chapter describes the enrichment and isolation of live CTCs from clinical blood samples for molecular characterization and other downstream applications.

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Xenograft as In Vivo Experimental Model,to identifying better treatment options. While the CSCs hypothesis highlights the need for a specific tumor target, patient-derived xenografts (PDXs) should also be considered for drug development as they better represent tumor heterogeneity and the environment in which a tumor develops.

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