Titlebook: Cancer Metastasis and the Lymphovascular System:; Basis for Rational T Stanley P. L. Leong Book 2007 Springer-Verlag US 2007 angiogenesis.a

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Hisayuki Mitsuo (researcher at IDE-JETRO)pproximately 80% of all lung cancer patients (5, 9). Surgery remains the gold standard treatment for locoregional NSCLC, and pathological lymph node (pN) status has remained the strongest clinical prognostic characteristic in early stages of operable NSCLC (21, 23). However, even in early stages, th

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https://doi.org/10.1007/978-3-642-58803-7hatic dominant model in which the regional lymph nodes served as filters for cancer cells. When the filter was filled, the cancer cells would move to the other lymph nodes and distant sites. The Halsted’s model (1) was then replaced by Fisher’s model in which all breast cancers were considered to be

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https://doi.org/10.1007/978-88-470-5379-3te key cellular functions in epithelial malignancies.After ligand binding, EGFR homo- or heterodimerizes with other members of the EGFR family of receptors, such as HER-2, and activates a signaling cascade that participates in tumor proliferation, angiogenesis, survival, and invasion/metastasis (61)

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Anatomy of the Human Lymphatic System,m initial lymphatics and lymph transport to progressively larger vessels (lymphatic collectors and trunks), finally reaching the confluence of the internal jugular and subclavian veins as lymphatic and thoracic ducts, respectively, at the right and left venous angles.

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Patterns of Metastasis in Human Solid Cancers,hatic dominant model in which the regional lymph nodes served as filters for cancer cells. When the filter was filled, the cancer cells would move to the other lymph nodes and distant sites. The Halsted’s model (1) was then replaced by Fisher’s model in which all breast cancers were considered to be systemic from their onset (2).