Titlebook: Cancer Chemo- and Immunopharmacology; 1. Chemopharmacology Georges Mathé,Franco M. Muggia Book 1980 Springer-Verlag Berlin Heidelberg 1980

ANTI

Vindesine: A New Vinca Alkaloid,xperimental neurotoxicity, and it inhibits the polymerization of tubulin. Its terminal half-life is 24 h and its plasma clearance is intermediate between those of vinblastine (VLB) and VCR. The maximal tolerated dose is 4–5 mg/m./week, the dose-limiting toxicity being myelosuppression (nadir by days

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,The Epipodophyllotoxin Derivatives VM-26 and VP-16-213, 1976–1979, a Review,od, but the greatest lethal effect is experienced in the late S and G. phases. In transplanted tumors both drugs have shown marked schedule dependency and human studies also support this..As a single agent VP 16-213 is among the most active drugs in small-cell carcinoma of the lung. Significant clin

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Finasteride

Pandemic

防水

1,2-Diaminocyclohexane Platinum Derivatives of Potential Clinical Value,ycin, adriamycin, Cytoxan (cyclophosphamide), vindesine, or the arabinosylcytosine (ara-C) derivatives. With these combinations, many investigators have reported on activity in germ cell tumors of the testis, carcinoma of the head and neck, penis, cervix, bladder, lung, esophagus, and ovary [1,7]. I

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Digest

Pers?nlichkeitsst?rung und Neurose associated with high-dose infusions, contribute to the chronic toxicity of MTX administration, and cross-react to a significant degree in radioimmunoassay methods for measurement of MTX concen- trations.

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Pers?nlichkeitsst?rung und Neuroset increased by the high-dose methotrexate, although the antitumor activity of the combination appears enhanced. Attempts at further increasing the intensity of this regimen or comparative trials with other therapy appears warranted.

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