Titlebook: Calcium-Binding Proteins of the EF-Hand Superfamily; From Basics to Medic Claus W. Heizmann Book 2019 Springer Science+Business Media, LLC,

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Deep Two-Photon Imaging In Vivo with a Red-Shifted Calcium Indicatorin anesthetized or awake behaving animals. Scientific insights about single-cell processing of sensory information but also analyses of higher cognitive functions in healthy or diseased states became thereby feasible. However, two-photon imaging is generally limited to depths of a few hundred microm

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Chaperoning Against Amyloid Aggregation: Monitoring In Vitro and In Vivos aimed at preventing the formation/elimination of protein aggregates are being developed to control these diseases. Molecular chaperones are a class of protein that not only direct the functionally relevant fold of the protein but also perform quality control against stress, misfolding/aggregation.

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Gene Transfer of Calcium-Binding Proteins into Adult Cardiac Myocyteslure results from poor myocardial relaxation and inadequate filling of the left ventricular chamber caused in part by calcium-handling dysregulation. In this chapter we describe methods to investigate new approaches of novel human Ca. binding protein motifs to restore normal Ca. handling function to