Titlebook: CNS Complications of Malignant Disease; J. M. A. Whitehouse (Director of the CRC Medical O Book 1979 The contributors 1979 central nervous

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Yves Dauvilliers,Giuseppe Plazzias been due in part to the use of central nervous system (CNS) ‘prophylaxis’ as well as effective systemic chemotherapy (Aur .., 1971,1972,1973; Hustu .., 1973; Simone .., 1975; Holland, 1976; Pinkel .., 1977).

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Lori A. Panossian,Alon Y. Avidanadditional CNS therapy, meningeal leukaemia recurs within a median time of around three months (Selawry and Odom, 1968; Sullivan .., 1975a). Recurrence can be delayed by maintenance monthly, or 6–8 weekly, intrathecal (IT) injections of methotrexate (MTX) (table 5.1), but permanent eradication of me

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Yves Dauvilliers,Giuseppe Plazziaemia (ALL). As shown by Pinkel (1973), Simone (1974) and by us (Pouillart .., 1972), the treatment of established CNSL is less successful than prophylaxis, and the occurrence of meningeal relapse is usually associated with a poor prognosis of the disease. It is now generally accepted that treatment

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Is Narcolepsy a Neurodegenerative Disorder?ion of the leptomeninges, extradural compression of the spinal cord and/or brain, and infiltration or compression of cranial and peripheral nerves. In addition, the lymphomas may be associated with such disorders as neuromuscular paraneoplastic syndromes, multifocal leukoencephalopathy, . or opportu