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Titlebook: Boundaries between Promotion and Progression during Carcinogenesis; Oscar Sudilovsky,Henry C. Pitot,Lance A. Liotta Book 1991 Plenum Press

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發(fā)表于 2025-3-28 18:36:38 | 只看該作者
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發(fā)表于 2025-3-28 20:11:45 | 只看該作者
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發(fā)表于 2025-3-29 01:16:01 | 只看該作者
Introduction to Loop TransformationsGordon Conference on Cancer in August, 1987. It had become evident to me and other participants that the concepts of promotion and progression as two separate stages in a multi-step model of carcinogenesis required further evaluation.
44#
發(fā)表于 2025-3-29 05:25:09 | 只看該作者
Introduction to Loop Transformationse stage of initiation as that which established “a persistent region of . whence tumors of varied kinds emerge at a later time”.. All of the remainder of neoplastic development he termed progression. In a sense, such a concept was quite analogous to that proposed earlier by several authors as the st
45#
發(fā)表于 2025-3-29 10:19:18 | 只看該作者
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發(fā)表于 2025-3-29 12:58:37 | 只看該作者
Introduction to Loop Transformationsnogenesis.. Although skin tumors can be induced by repeated topical applications of a carcinogen., protocols have been developed which define at least three distinct stages: initiation, promotion and malignant conversion.. In a typical experiment, the first stage, initiation, is accomplished by a si
47#
發(fā)表于 2025-3-29 15:57:12 | 只看該作者
Introduction to Loop Transformations this work are: what causes breast cancer? how does breast cancer start? what determines the susceptibility of the gland to undergo carcinogenesis? what makes an initiated cell progress to a fully malignant one?
48#
發(fā)表于 2025-3-29 20:33:09 | 只看該作者
49#
發(fā)表于 2025-3-30 01:05:20 | 只看該作者
https://doi.org/10.1057/9780230514768h (1953), and of recalling many pleasant and stimulating discussions with each of them. Foulds studied solid tumors, primarily adenocarcinomas of the breast, and his definition of progression as the independent and irreversible gain or loss of unit characters with time leading to the autonomous stat
50#
發(fā)表于 2025-3-30 05:42:00 | 只看該作者
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