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Titlebook: Biomarkers in Breast Cancer; Giampietro Gasparini,Daniel F. Hayes Book 2006 Humana Press 2006 DNA.classification.gene expression.systemic

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發(fā)表于 2025-3-21 18:06:24 | 只看該作者 |倒序瀏覽 |閱讀模式
期刊全稱Biomarkers in Breast Cancer
影響因子2023Giampietro Gasparini,Daniel F. Hayes
視頻videohttp://file.papertrans.cn/188/187804/187804.mp4
發(fā)行地址Includes supplementary material:
學(xué)科分類Cancer Drug Discovery and Development
圖書封面Titlebook: Biomarkers in Breast Cancer;  Giampietro Gasparini,Daniel F. Hayes Book 2006 Humana Press 2006 DNA.classification.gene expression.systemic
影響因子Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
Pindex Book 2006
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Urokinase-Type Plasminogen Activator and PAI-1 factors has the potential to result in the enhanced management of patients with breast cancer. Measurement of these analytes should thus be now considered for use in the routine management of patients with breast cancer.
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Predictive Value of c-,B2 for Endocrine Therapy and Chemotherapy in Breast Cancer, other regimens should not be withheld from women who cannot receive an anthracyline. Current clinical data also suggest a possible sensitivity to taxane-based therapy, especially when combined with an anthracycline. Trastuzumab-based therapy should be considered as first line therapy for women wit
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Circulating Vascular Endothelial Growth Factore with each other due to a lack of standardization of the pre-analytical phase. The chapter presents the main studies concerning anti-VEGF therapies; several studies evaluated the safety profile and activity of the combination of standard chemotherapy with new antiangiogenic agents. However, to date
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