Titlebook: Basic Principles of Cancer Chemotherapy; Kenneth C. Calman,John F. Smyth,Martin H. N. Tatte Textbook 1980Latest edition Macmillan Publishe

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Fibrin

Tumour Biology in Relation to Chemotherapy,tumours, even those from the same organ, may vary in their biological activity. Cancer may also be defined as an abnormal accumulation of transformed cells which grow and spread and which do not respond in a normal way to the growth-regulating systems of the organism. Such a simple definition, howev

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NOCT

Drug Development and Screening,fects of sulphur mustard gas as used in World War I, the modern era of cancer chemotherapy began in the 1940s with the demonstration that nitrogen mustard produced responses in malignant lymphoma. At about the same time, the antibacterial activity of para-aminobenzene sulphonamide was shown to be du

kidney

Staging, Evaluation of Treatment and Prognostic Factors,it has become necessary to define the extent of tumour spread. Tumour staging, therefore, can be used to determine those patients who may require chemotherapy. As a corollary, it may be also used to define those patients who may . require systemic therapy, because the tumour is localised.

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Esophagus

Immunological Aspects of Cancer Chemotherapy,sponsiveness prior to commencement of chemotherapy. Secondly, chemotherapy itself may markedly influence the immune response. Finally, chemotherapy and immunotherapy may be used together in the treatment of specific neoplasms. Before discussing these in detail, it is pertinent to review the immune r