Titlebook: Bacterial Multidrug Exporters; Methods and Protocol Akihito Yamaguchi,Kunihiko Nishino Book 2018 Springer Science+Business Media, LLC 2018

JADE

書目名稱Bacterial Multidrug Exporters影響因子(影響力)




書目名稱Bacterial Multidrug Exporters影響因子(影響力)學(xué)科排名




書目名稱Bacterial Multidrug Exporters網(wǎng)絡(luò)公開度




書目名稱Bacterial Multidrug Exporters網(wǎng)絡(luò)公開度學(xué)科排名




書目名稱Bacterial Multidrug Exporters被引頻次




書目名稱Bacterial Multidrug Exporters被引頻次學(xué)科排名




書目名稱Bacterial Multidrug Exporters年度引用




書目名稱Bacterial Multidrug Exporters年度引用學(xué)科排名




書目名稱Bacterial Multidrug Exporters讀者反饋




書目名稱Bacterial Multidrug Exporters讀者反饋學(xué)科排名

刺激

Crystallographic Analysis of Drug and Inhibitor-Binding Structure of RND-Type Multidrug Exporter AcrMurakami et al., Nature 443:173–179, 2006; Nakashima et al., Nature 480:565–569, 2011; Nakashima et al., Nature 500:120–126, 2013). Analyses revealed the existence of a specific mechanism to recognize numerous substrates that the multisite binding is the base of multidrug recognition rather than ind

BIBLE

Generation of Conformation-Specific Antibody Fragments for Crystallization of the Multidrug Resistannizing the native conformation of a major facilitator superfamily (MFS)-type MDR transporter MdfA from .. We confirmed that the use of Fab fragments was efficient for stabilization of MdfA and improvement of its crystallization properties.

infelicitous

Covalently Linked Trimers of RND (Resistance-Nodulation-Division) Efflux Transporters to Study Theirnvolved in proton relay, or in “real time” by using a protein in which one protomer contains two Cys residues on both sides of the large cleft in the periplasmic domain and then by rapidly inactivating this protomer with a methanethiosulfonate cross-linker.

刪減

Molecular Modeling of Multidrug Properties of Resistance Nodulation Division (RND) Transportersmics simulations and in silico free energy estimations can all together give precious insights into the processes of recognition and extrusion of substrates, as well as on the possible inhibition strategies.

膽汁

粗魯?shù)娜?/a>

https://doi.org/10.1007/978-3-658-19558-8nizing the native conformation of a major facilitator superfamily (MFS)-type MDR transporter MdfA from .. We confirmed that the use of Fab fragments was efficient for stabilization of MdfA and improvement of its crystallization properties.

脆弱帶來

輕快來事

https://doi.org/10.1007/978-3-476-05869-0mics simulations and in silico free energy estimations can all together give precious insights into the processes of recognition and extrusion of substrates, as well as on the possible inhibition strategies.

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