Titlebook: Bacterial Genomes and Infectious Diseases; Voon L. Chan,Philip M. Sherman,Billy Bourke Book 2006 Humana Press 2006 Microarray.antibiotics.

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Genomic Approach to Understanding Infectious Disease Mechanisms,notated as proteins with no known function. When genomic sequences of virulent and nonvirulent strains of a particular species are available, comparative genomic analysis is a powerful tool to identify putative virulence genes. Variation in virulence between strains of the same species is a common p

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Knockout and Disease Models in Toll-Like Receptor-Mediated Immunity,arious microorganisms, including bacteria and viruses. Innate immune responses are highly conserved throughout evolution, and one important family of sensors responsible for initiating innate immune responses in mammals, the Toll-like receptors (TLRs), has recently been discovered. In this chapter,

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Genomics of , Species,ost frequent bacterial infection of humanity, causes peptic ulcer disease and gastric cancer. Other . species are emerging as causes of infection, inflammation, and cancer in the intestine, liver, and biliary tract, although the true prevalence of these enterohepatic . species in humans is not yet k

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Mycobacterial Genomes,iated with immunocompromised individuals. The availability of whole-genome sequences of mycobacterial species in the past several years has revolutionized TB research. This chapter provides an overview of the biology of mycobacteria and the diseases that they cause, with emphasis on how recent advan

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