Titlebook: Autophagy Networks in Inflammation; Maria Chiara Maiuri,Daniela De Stefano Book 2016 Springer International Publishing Switzerland 2016 au

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Laura L. Parrilla,Celia Escamilla-Riveraammatory and autoimmune pathologies. These complex disorders result from a combination between genetic and environmental factors. A clear genetic link between Crohn’s disease and autophagy deregulation has been demonstrated. Autophagy deregulation provoked by environmental triggers like nutrient exc

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En Route to Quantum Field Theorylasmic proteins or damaged organelles to maintain normal cell homeostasis. Recent evidence suggests the involvement of autophagy in synaptic plasticity, in addition to its crucial role in the quality control of proteins and organelles in neurons. Thus an impairment of the autophagic machinery is clo

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S. Svitlov,C. Rothleitner,L.J. Wang, whereas others claim a lipogenic function. This chapter aims to give an update of the present knowledge (last 5 years) on autophagy in the hepatic lipid metabolism, hepatic insulin resistance, steatohepatitis and hepatic fibrogenesis. An improved understanding of the autophagic process should lead

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1422-7746 tions ofthe autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysreg978-3-319-80719-5978-3-319-30079-5Series ISSN 1422-7746 Series E-ISSN 2296-4525

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The Complex Crosstalk Between Autophagy and ROS Signalling Pathwaysof damaged mitochondria and oxidized cellular substrates and by modulating activity of the detoxifying antioxidant systems. ROS are also involved in the initiation of inflammation, a process that required the secretion of several inflammatory mediators. Here, we will discuss the regulation of inflam

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Interplay Between Autophagy and Inflammasomesy in innate immune response. Many of the newly uncovered links between autophagy and inflammasome have raised new questions about the mechanism controlling inflammasome function, which are highlighted in this chapter.