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Titlebook: Antirheumatic Therapy: Actions and Outcomes; Richard O. Day,Daniel E. Fürst,Barry Bresnihan Book 2005 Birkh?user Basel 2005 Arthritis.auto

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發(fā)表于 2025-3-21 18:01:21 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Antirheumatic Therapy: Actions and Outcomes
影響因子2023Richard O. Day,Daniel E. Fürst,Barry Bresnihan
視頻videohttp://file.papertrans.cn/159/158659/158659.mp4
發(fā)行地址Comprehensive and well structured according to classes of agents.Includes an outlook on future molecular targets.International authorship
學(xué)科分類Progress in Inflammation Research
圖書封面Titlebook: Antirheumatic Therapy: Actions and Outcomes;  Richard O. Day,Daniel E. Fürst,Barry Bresnihan Book 2005 Birkh?user Basel 2005 Arthritis.auto
影響因子Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short- term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor- der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi- cian‘s opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, quality of life and impact on broad domains of health have been given increasing emphasis. Also, the significance of early treatment of RA in order to optimise long-term outcomes has a relatively short history [1]. We have been focussed on the disease processes as surrogates for long- term outcomes. Until the short-term process measures are validated as surrogates of long-term effects we should also turn our attention to outcomes of disease and the impact of our management on those outcomes [2)
Pindex Book 2005
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Progress in Inflammation Researchhttp://image.papertrans.cn/a/image/158659.jpg
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Multiscale , Modeling of Cartilage Injuriesll drugs, the chemical properties of the DMARD and corticosteroids are important aspects of their pharmacology. In this chapter, the medicinal chemistry of the various DMARD is discussed. The coverage includes the chemical factors that affect their handling by the body. In addition to the DMARD disc
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Brianne K. Connizzo,Lin Han,Robert L. Sahheir patients are faced with a variety of therapeutic choices in the management of RA and must make decisions about specific disease-modifying antirheumatic drugs (DMARDs), including potential combinations of different agents. A careful balance of short-term and long-term benefits and risks must be
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https://doi.org/10.1007/978-3-319-48899-8ponse. However, biologic agents are frequently immunogenic, requiring complex and labor intensive production processes and parenteral administration, resulting in high costs which limit both availability and access to treatment.
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Advances in Applied Neurological Sciences 6-mercaptopurine and this is metabolised by hypoxanthine guanine phosphoribosyl transferase (HGPRT) to produce the active metabolites thioinosinic and thioguanylic acid. These metabolites inhibit intracellular function by interfering with adenine and guanine ribonucleotide production through suppre
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