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Titlebook: Antiepileptic Drug Discovery; Novel Approaches Alan Talevi,Luisa Rocha Book 2016 Springer Science+Business Media New York 2016 Antiepilepto

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41#
發(fā)表于 2025-3-28 14:58:08 | 只看該作者
Erythropoietin as Potential Neuroprotective and Antiepileptogenic Agent in Epilepsy and Refractory Egh doses of EPO could also reduce the brain damage that results from seizure activity seen in the epileptogenic process subsequent to status epilepticus and perhaps avoids sudden unexpected death in epilepsy (SUDEP).
42#
發(fā)表于 2025-3-28 19:26:18 | 只看該作者
Caloric Restriction and Dietary Treatments of Epilepsy: Mechanistic Insights for Drug Discoveryalthough several possibilities have been suggested. Each of its proposed mechanisms of action can be targeted for the discovery of drugs that prevent or modify epilepsy. This chapter briefly describes every one of the food modifications in current clinical use or that has been studied using animal m
43#
發(fā)表于 2025-3-29 00:58:27 | 只看該作者
Gene Therapy in Epilepsywhich exerts neuroprotective and anticonvulsive actions. Recombinant adeno-associated viral vectors can release any of these agents because of their neuronal tropism, lack of toxicity, and stable persistence in neurons. This chapter provides an overview of gene therapy methods, and reviews several s
44#
發(fā)表于 2025-3-29 04:17:29 | 只看該作者
45#
發(fā)表于 2025-3-29 07:30:43 | 只看該作者
Nanoformulations of Antiepileptic Drugs: In Vitro and In Vivo Studiesed situation is far beyond the possibilities of the present book chapter, and the sanitary problem of epilepsy (as well as other CNS diseases treated with anticonvulsant drugs) has already been described in the previous chapters. Hence, we will focus in the pharmacokinetic aspects of the problem of
46#
發(fā)表于 2025-3-29 14:29:54 | 只看該作者
Angaben aus der Festigkeitslehre,of the role of SV2A in epilepsy, addressing three main issues: SV2A function in neurotransmission, the correlation of the expression and/or distribution of the protein with treatment response and neuronal damage, and the reasons that SV2A is a good molecular target for the discovery of new antiepile
47#
發(fā)表于 2025-3-29 16:21:43 | 只看該作者
https://doi.org/10.1007/978-3-662-25897-2harmacological blockade of glutamatergic signaling represents an attractive alternative for the control of seizures and neuroprotection. In particular, glutamate receptors are attractive targets for novel antiepileptic drugs because different studies have demonstrated that its agonists and antagonis
48#
發(fā)表于 2025-3-29 21:18:02 | 只看該作者
49#
發(fā)表于 2025-3-30 00:34:21 | 只看該作者
Angaben aus der Festigkeitslehre,gh doses of EPO could also reduce the brain damage that results from seizure activity seen in the epileptogenic process subsequent to status epilepticus and perhaps avoids sudden unexpected death in epilepsy (SUDEP).
50#
發(fā)表于 2025-3-30 05:03:32 | 只看該作者
https://doi.org/10.1007/978-3-662-12947-0although several possibilities have been suggested. Each of its proposed mechanisms of action can be targeted for the discovery of drugs that prevent or modify epilepsy. This chapter briefly describes every one of the food modifications in current clinical use or that has been studied using animal m
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