Titlebook: Animal Models of Allergic Disease; Methods and Protocol Kumi Nagamoto-Combs Book 2021 Springer Science+Business Media, LLC, part of Springe

無畏

Generation and Characterization of Inducible Lung and Skin-Specific IL-22 Transgenic Mice,rtTA/TRE-Tight-IL-22 (CC10-rtTA-IL-22) or SPC-rtTA/TRE-Tight-IL-22 (SPC-rtTA-IL-22) mice, do not produce detectable levels of IL-22 in their bronchoalveolar lavage (BAL) samples in the absence of doxycycline (Dox). However, oral Dox treatment of these mice induces IL-22 expression in the BAL, and th