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Titlebook: Amorphous Drugs; Benefits and Challen Marzena Rams-Baron,Renata Jachowicz,Marian Paluch Book 2018 Springer International Publishing AG 2018

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21#
發(fā)表于 2025-3-25 07:17:28 | 只看該作者
22#
發(fā)表于 2025-3-25 09:54:43 | 只看該作者
Why Amorphous Drugs?,olubility, intestinal permeability) becomes a great challenge and a bottleneck in drug development. Statistically, more than 40% of approved drugs and even 70–90% of those under investigations are poorly water-soluble and additional efforts are required to improve their water solubility [3–5].
23#
發(fā)表于 2025-3-25 15:21:30 | 只看該作者
24#
發(fā)表于 2025-3-25 17:33:49 | 只看該作者
https://doi.org/10.1007/978-3-642-86294-6olubility, intestinal permeability) becomes a great challenge and a bottleneck in drug development. Statistically, more than 40% of approved drugs and even 70–90% of those under investigations are poorly water-soluble and additional efforts are required to improve their water solubility [3–5].
25#
發(fā)表于 2025-3-25 23:55:29 | 只看該作者
Die Einengung der Anwendungsm?glichkeitenion, if successful. A poorly water soluble drug candidate not only may lengthen the formulation development phase, increase the resource demands, delay the clinical trials due to insufficient in vivo exposure, but also may impact the ultimate success of the entire program due to suboptimal bioavailability [3].
26#
發(fā)表于 2025-3-26 01:30:48 | 只看該作者
https://doi.org/10.1007/978-3-642-86294-6s extensive knowledge of materials, current technological processes and regulations. Bearing in mind that the form of drug should be suitable for the administration route and safe to apply, understanding of manufacturing process is of key importance to successful dosage form development.
27#
發(fā)表于 2025-3-26 05:57:44 | 只看該作者
Amorphous Drug Solubility and Absorption Enhancement,s extensive knowledge of materials, current technological processes and regulations. Bearing in mind that the form of drug should be suitable for the administration route and safe to apply, understanding of manufacturing process is of key importance to successful dosage form development.
28#
發(fā)表于 2025-3-26 08:28:28 | 只看該作者
https://doi.org/10.1007/978-3-642-86294-6 groups, that are termed space symmetry groups. [3] A periodic structure can then be described only by defining the crystallographic coordinates of an asymmetric unit and the symmetry operations of the space symmetry group.
29#
發(fā)表于 2025-3-26 14:02:46 | 只看該作者
Order vs. Disorder in the Solid State, groups, that are termed space symmetry groups. [3] A periodic structure can then be described only by defining the crystallographic coordinates of an asymmetric unit and the symmetry operations of the space symmetry group.
30#
發(fā)表于 2025-3-26 19:25:30 | 只看該作者
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