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Titlebook: Amine Oxidases and Their Impact on Neurobiology; Proceedings of the 4 Peter Riederer,Moussa B. H. Youdim Conference proceedings 1990 Spring

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發(fā)表于 2025-3-21 18:22:42 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
期刊全稱Amine Oxidases and Their Impact on Neurobiology
期刊簡(jiǎn)稱Proceedings of the 4
影響因子2023Peter Riederer,Moussa B. H. Youdim
視頻videohttp://file.papertrans.cn/155/154675/154675.mp4
學(xué)科分類Journal of Neural Transmission. Supplementa
圖書封面Titlebook: Amine Oxidases and Their Impact on Neurobiology; Proceedings of the 4 Peter Riederer,Moussa B. H. Youdim Conference proceedings 1990 Spring
Pindex Conference proceedings 1990
The information of publication is updating

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沙發(fā)
發(fā)表于 2025-3-21 22:05:50 | 只看該作者
板凳
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Problemstellung und Zielsetzungne deprenyl binding. A high dose of unlabelled deprenyl was then administered to inhibit the enzyme and tracer doses of . C-L-deprenyl, with subsequent PET analyses, were given at 0, 2, 7, 21 and 42 days. The half-life for the turnover rate calculated was found to be 6.5 days.
地板
發(fā)表于 2025-3-22 08:24:13 | 只看該作者
5#
發(fā)表于 2025-3-22 10:25:36 | 只看該作者
https://doi.org/10.1007/978-3-658-34957-8and time-dependence of the inhibiton were also established in each case. The kinetic parameters defining non-covalent complex formation and covalent adduct formation were calculated for the mechanism-based inhibition of both MAO-A and MAO-B by these compounds.
6#
發(fā)表于 2025-3-22 16:51:20 | 只看該作者
https://doi.org/10.1007/978-3-476-03712-1 B type of MAO was found. Influence of substrate structure on its biotransformation effectiveness is realized by the principle — “better binding-worse catalysis”. MAO inactivation during the reaction is appeared to be realized as result of product inhibition and perhaps of substrate inhibition.
7#
發(fā)表于 2025-3-22 17:27:16 | 只看該作者
8#
發(fā)表于 2025-3-22 22:23:11 | 只看該作者
Molecular neuroanatomy of MAO-A and MAO-Bs in human post-mortem brain. Furthermore, using in situ hybridization histochemistry, locus coeruleus and raphé neurons in the human brain were found to code for MAO-A and MAO-B respectively and not vice versa.
9#
發(fā)表于 2025-3-23 02:03:44 | 只看該作者
10#
發(fā)表于 2025-3-23 06:02:18 | 只看該作者
Effect of selective and reversible MAO inhibitors on dopamine outflow in rat striatum: a microdialysnd homovanillic acid (HVA) was studied in the rat by transstriatal microdialysis. Reversible MAO-A inhibitors markedly increased the output of DA and concomitantly decreased the output of DOPAC and HVA. These effects were absent with the highly selective MAO-B inhibitor Ro 19-6327.
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