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Titlebook: Advances in Systems Biology; Igor I. Goryanin,Andrew B. Goryachev Conference proceedings 2012 The Editor(s) (if applicable) and The Author

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Lecture Notes in Computer Sciencew prominent classes of modular approaches based on formal network representations. Despite some promising research directions, several important theoretical challenges remain open on the way to formal, function-centered modular decompositions for dynamic biological networks.
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Reification and Truthmaking Patternsto study how the responses (the activated substrates) vary as a function of the available amounts of substrates, kinase, and phosphatases. Our results provide insight into how the cascade response is affected by crosstalk and external regulation.
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Modular Analysis of Biological Networksw prominent classes of modular approaches based on formal network representations. Despite some promising research directions, several important theoretical challenges remain open on the way to formal, function-centered modular decompositions for dynamic biological networks.
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