Titlebook: Acute Myeloid Leukemia; Christoph R?llig,Gert J. Ossenkoppele Book 2021 Springer Nature Switzerland AG 2021 Acute Myeloid Leukemia.Genomic

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Other Human Rights in Aviation Securityements in therapeutic options, until recently. A swathe of new drug approvals by the FDA has resulted in a subset of drugs also receiving approval in the European Union (EMA). These drugs have been discussed elsewhere in this book. This chapter will focus on new, non-immune-based therapies which hav

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https://doi.org/10.1007/978-3-030-91194-2aNet (ELN) recommendations (Dohner et al. 2017)..This chapter intends to offer background information on germline predisposition to MN and provide the hematologist with practical guidelines on when to suspect, how to detect, and what to consider in the treatment and follow-up of patients carrying genetic predisposition to MN.

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Aviation Noise Impact Management presence of at least 20% of myeloid blasts in BM or PB..Careful genetic assessment, together with evaluations of performance status and comorbidities, is recommended to characterize disease-specific and patient-specific factors providing important information for risk stratification and treatment decisions.

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Importance of Fatigue Risk Managemente based on the probability to achieve a response to intensive or investigational salvage therapy. Several new approaches are currently evaluated and matching for controls may help to increase external validity of new approaches evaluated in single arm phase-II clinical trials.

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https://doi.org/10.1007/978-3-642-11703-9able safety profile as compared to what we have learned so long with intensive chemotherapy in R/R AML. Other small molecules targeting BCL2 or TP53, drug combinations, or monoclonal antibodies are also intensively studied in these patients paving the way for significant prognosis improvement in the coming years.

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