Titlebook: A Systems Biology Approach to Blood; Seth Joel Corey,Marek Kimmel,Joshua N. Leonard Book 2014 The Editor(s) (if applicable) and The Author

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https://doi.org/10.1007/978-3-662-45940-9 CCAAT/enhancer-binding protein (C/EBPα; alpha), C/EBPε (epsilon), and growth factor independent-1 (Gfi-1). We also review granulocyte colony-stimulating factor (G-CSF) receptor-induced signal transduction pathways, their influence on proliferation and differentiation, and the cooperativity of cytokines and chemokines in this process.

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Current Chinese Economic Report Seriesining HSC self-renewing versus blood-lineage-reconstituting divisions. In this chapter, we integrate these findings and highlight the cellular networks that control HSC function and fitness by regulating HSC cycling.

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https://doi.org/10.1007/978-981-10-0167-3uce long-term drug resistance. Thus, a recent mathematical model taking into account the complex dynamics of the leukemic stem-like cells is described. The chapter closes with a few applications of this model to chronic myeloid leukemia.

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https://doi.org/10.1007/978-3-662-45940-9ent of multi-scale models coupling processes at several scales and running predictive model simulations on powerful computer clusters can help interdisciplinary groups of researchers to suggest and test new patient-specific treatment strategies.

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