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W. Creutzfeldtrug correlates best with therapeutic effect. The free drug in plasma is in equilibrium with protein-bound drug and, because of this relationship, it is important to understand to what extent a particular drug is protein-bound. Various attempts to measure free drug concentration in saliva (.) and cer

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The Categories of States,her categories are indicated by the use of such terms, applied to states, as ‘residual’,’ successor’, ‘neutral’, ‘unaligned’ and ‘buffer’, each of which throws one ray of light on their diversity. It need hardly be added that these various classifications are not mutually exclusive and that each embraces variant forms.

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